| 16/10/2021 |  |
Clermont FootClermont | 1 | x | 0 | LilleLille |  |
||
| 17/10/2021 |  |
BrestBrest | 1 | x | 1 | Stade de ReimsReims |  |
||
| 22/10/2021 |  |
Saint-ÉtienneSaint-Étienne | 2 | x | 2 | AngersAngers |  |
||
| 23/10/2021 | |
LilleLille | 1 | x | 1 | BrestBrest | |
||
| 24/10/2021 |  |
NiceNice | 3 | x | 2 | LyonLyon |  |
||
| 24/10/2021 |  |
LensLens | 4 | x | 1 | MetzMetz |  |
||
| 24/10/2021 |  |
Stade RennaisStade Rennais | 1 | x | 0 | StrasbourgStrasbourg |  |
||
| 24/10/2021 |  |
LorientLorient | 1 | x | 1 | BordeauxBordeaux |  |
||
| 24/10/2021 |  |
AS MonacoAS Monaco | 3 | x | 1 | MontpellierMontpellier |  |
||
| 24/10/2021 |  |
MarseilleMarseille | 0 | x | 0 | Paris Saint-GermainPSG |  |